Selected Goodwin Biotechnology Publications on Bioconjugation
Sesay M. Development, Manufacture and Preclinical evaluation and efficacy studies of a melanin IgM antibody labeled with Rhenium-188-Labeled against experimental human metastatic melanoma in nude mice. Second Annual Protein Engineering Summit. 2009.
E. Dadachova, E. Revskaya, M. Sesay, R. Howell, G. Thornton, et al., Pre-clinical development of a 188-Re labeled melanin-binding antibody for phase I clinical trial in patients with metastatic melanoma. J Nuclear Medicine. 2008; 49 (Supplement): 327P.
E. Dadachova, E. Revskaya, M. Sesay, H. Damania, R.Boucher et al., Pre-clinical evaluation and efficacy studies of a melanin-binding IgM antibody with 188-Re against experimental human metastatic melanoma in nude mice. Cancer Biology and Therapy. 2008; 7(7): 1116-1127.
E, Revskaya E, Sesay MA, et al. Melanin-binding antibody radiolabeled
with therapeutic radionuclide Re188 pre-clinical in vitro and in vivo
development for Phase I clinical trial in patients with metastatic
melanoma. Proceedings of the 6th International Symposium on the Targeted
Anticancer Therapies. Bethesda, MD, USA, March 20-22,2008.
Revskaya E, Dadachova E, Sesay SA, et al. Pre-clinical development of a melanin-binding IgM antibody labeled with Re188 for Phase I clinical trial in patients with metastatic melanoma pigment. Cell Res. 2007; 20(6): 520-521.
Sesay, M.A. Monoclonal Antibody Conjugation via Chemical Modification. BioPharm International. 2003; December; 32-39.
Steve Pincus, et. al. Evaluation of Antigen based Heteropolymer (AHP) for Treatment of Systemic Lupus Erythematosus in a Non-Human Primate Model. Clinical Immunology. 2002; 105: 141-154.
E. Dadachova, A Casadevall, M. Sesay, H. Damania, and P. Smariga, Radiolabeled monoclonal antibodies using TCEP, and uses thereof. US Patent Application number 61/000,795; 2008. (Patent Pending); Also patent pending filed with World, Canada, Australia, Japan, Europe and other countries.
E. Dadachova, A Casadevall, M. Sesay, H. Damania, and P. Smariga, Disposable column system for purification of radiolabelled polypeptides. World Intellectual Property Organization Patent, 2009, Publication number WO/2009/058737, Application number PCT/US2008/081337; Also patent pending filed with US, Canada, Australia, Japan, Europe and others
Selected Publications on Bioconjugation in which Goodwin Biotechnology was mentioned
Klein M, Lotem M, Peretz T, et al. Safety and Efficacy of 188-Rhenium-Labeled Antibody to Melanin in Patients with Metastatic Melanoma. Journal of Skin Cancer. Vol. 2013; Article ID 828329, 8 pages, 2013.